Chetomin

Catalog # Availability Size / Price Qty
4705/1
Cat.No. 4705 - Chetomin | C31H30N6O6S4 | CAS No. 1403-36-7
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Description: Blocks interaction of HIF-1α, HIF-2α and STAT2 with CBP/p300

Chemical Name: (3S,5aR,10bS,11aS)-2,3,5a,6,10b,11-hexahydro-3-(hydroxymethyl)-10b-(3-[(1S,4S)-3-[[4-(hydroxymethyl)-5,7-dimethyl-6,8-dioxo-2,3-dithia-5,7-diazabicyclo[2.2.2]oct-1-yl)methyl]-1H-indol-1-yl]-2-methyl-3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione

Purity: ≥98%

Product Details
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Biological Activity

Targets the CH1 domain of CBP/p300; inhibits interaction of HIF-1α, HIF-2α and STAT2 with CBP/p300. Attenuates hypoxia-induced gene expression in vitro and in vivo; radiosensitizes human HT 1080 fibrosarcoma cells in vitro.

Technical Data

M.Wt:
710.87
Formula:
C31H30N6O6S4
Solubility:
Soluble in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1403-36-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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