Chlorisondamine diiodide
Tocris Bioscience | Catalog # 1001
Key Product Details
Description
Alternative Names
Product Description
An exceptionally long lasting nicotinic antagonist (IC50 ~ 1.6 mM); blockade of central nicotinic responses induced by chlorisondamine can persist for several weeks.
Product Specifications for Chlorisondamine diiodide
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 6.12 | 10 |
Preparing Stock Solutions for Chlorisondamine diiodide
The following data is based on the product molecular weight 611.95.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.34 mL | 81.71 mL | 163.41 mL |
| 0.5 mM | 3.27 mL | 16.34 mL | 32.68 mL |
| 1 mM | 1.63 mL | 8.17 mL | 16.34 mL |
| 5 mM | 0.33 mL | 1.63 mL | 3.27 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 52 publications citing the usage of this product.
- El-Bizri and Clarke Blockade of nicotinic receptor-mediated release of DA from striatal synaptosomes by chlorisondamine and other nicotinic antagonists administered in vitro. Br.J.Pharmacol. 1994 PMID: 8004384
- El-Bizri and Clarke Regulation of nicotinic receptors in rat brain following quasi-irreversible nicotinic blockade by chlorisondamine and chronic treatment with nicotine. Br.J.Pharmacol. 1994 PMID: 7858886
- Clarke The pharmacology of the nicotinic antagonist, chlorisondamine investigated in rat brain and autonomic ganglion. Br.J.Pharmacol. 1994 PMID: 7911713
Product Documents for Chlorisondamine diiodide
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Chlorisondamine diiodide
For research use only
Related Research Areas
Citations for Chlorisondamine diiodide
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