Chlorisondamine diiodide

  ( 3 citations )    
Product Datasheet
Catalog Number:1001
Alternate Names:3-[[4-(Chlorophenyl)piperazin-1-yl]methyl-1H-pyrrolo[2,3-b]pyridine diiodide
Chemical Name:4,5,6,7-Tetrachloro-1,3-dihydro-2-methyl-2-[2-trimethylammonium)ethyl]-2H-isoindolium diiodide
Product Details
Citations (3)
Reviews
Biological Activity
An exceptionally long lasting nicotinic antagonist (IC50 ~ 1.6 mM); blockade of central nicotinic responses induced by chlorisondamine can persist for several weeks.
Technical Data
  • M.Wt:
    611.95
  • Formula:
    C14H20Cl4I2N2
  • Solubility:
    Soluble to 10 mM in water
  • Purity:
    >99
  • Storage:
    Desiccate at +4°C
  • CAS No:
    96750-66-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Chlorisondamine diiodide include:

3 Citations: Showing 1 - 3
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  1. Angiotensin-dependent autonomic dysregulation precedes dilated cardiomyopathy in a mouse model of muscular dystrophy.
    Authors: Sabharwal Et al.
    J Exp Med  2015;100:776
  2. Chronic oral administration of Ang-(1-7) improves skeletal muscle, autonomic and locomotor phenotypes in muscular dystrophy.
    Authors: Sabharwal Et al.
    J Cereb Blood Flow Metab  2014;127:101
  3. Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve.
    Authors: Luyer Et al.
    Clin Sci (Lond)  2005;202:1023

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