Chemical Name: 2,4-Dichloro-N-(phenylcarbamoyl)phenylbenzamide
Biological ActivityGPR27 agonist. Promotes recruitment of β-arrestin 2 to chimeric GPR27V2 and wild-type GPR27 in a firefly luciferase complementation assay (pEC50 values are 6.34 and 5.1, respectively).
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Activation of the orphan G protein-coupled receptor GPR27 by surrogate ligands promotes β-arrestin 2 recruitment.
Dupuis et al.
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