CID 2745687

Tocris Bioscience | Catalog # 4293

GPR35 antagonist
Tocris Bioscience

Key Product Details

Description

GPR35 antagonist
View all Orphan 7-TM Receptor Antagonists »

Product Description

CID 2745687 is a competitive, reversible antagonist of the orphan receptor GPR35 (Ki = 12.8 nM). Blocks the GPR35-mediated increase in ERK1/2 phosphorylation and β-arrestin recruitment induced by pamoic acid.

Product Specifications for CID 2745687

Molecular Weight

395.43

Formula

C17H19F2N5O2S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

1-(2,4-Difluorophenyl)-5-[[2-[[(1,1-dimethylehyl)amino]thioxomethyl]hydrazinylidene]methyl]-1H-pyrazole-4-carboxylic acid methyl ester

CAS Number

264233-05-8

PubChem ID

9581011

InChI Key

CYNLZIBKERMMOA-AWQFTUOYSA-N

SMILES

FC1=CC(F)=CC=C1N2C(/C=N/NC(NC(C)(C)C)=S)=C(C(OC)=O)C=N2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.54 100
Ethanol 3.95 10

Preparing Stock Solutions for CID 2745687

The following data is based on the product molecular weight 395.43.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.53 mL 12.64 mL 25.29 mL
5 mM 0.51 mL 2.53 mL 5.06 mL
10 mM 0.25 mL 1.26 mL 2.53 mL
50 mM 0.05 mL 0.25 mL 0.51 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 11 publications citing the usage of this product.

Product Documents for CID 2745687

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CID 2745687

For research use only

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