Dual L- and N-type calcium channel blocker that displays antihypertensive, sympatholytic and neuroprotective activity. Lowers mean blood pressure and reduces the size of cerebral infarction in the rat model of focal brain ischemia.
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Neuroprotective effects of a dual L/N-type Ca2+ channel blocker cilnidipine in the rat focal brain ischemia model.
Takahara et al.
Preferential inhibition of L- and N-type calcium channels in the rat hippocampal neurons by cilnidipine.
Murai et al.
Brain Res., 2000;854:6
The evaluation of the N-type channel blocking properties of cilnidipine and other voltage-dependent calcium antagonists.
Nap et al.