Catalog Number: 1692
Chemical Name: 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
Biological Activity
Potent phosphodiesterase III A (PDE3A) inhibitor (IC50 = 0.2 μM) and inhibitor of adenosine uptake. Has antimitogenic, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.
Technical Data
  • M.Wt:
    369.47
  • Formula:
    C20H27N5O2
  • Solubility:
    Soluble to 10 mM in ethanol and to 50 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    73963-72-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The pharmacology of cilostazol.
    Schror
    Diabetes Obes.Metab., 2002;4:S14
  2. General pharmacological properties of cilostazol, a new antithrombotic drug. Part I: effects on the central nervous system.
    Shintani et al.
    Arzneimittelforschung, 1985;35:1157
  3. General pharmacological properties of cilostazol, a new antithrombotic drug. Part II: effects on the peripheral organs.
    Shintani et al.
    Arzneimittelforschung, 1985;35:1163

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