Chemical Name: 3,4-Dihydro-N-(5-methyl-3-isoxazolyl)-α-phenyl-1(2H)-quinolineacetamide
Biological ActivitySelective TRPM3 agonist. Exhibits selectivity for TRPM3 over TRPM1, TRPM2 and TRPM4-8. Stimulates insulin release from pancreatic islet cells in vitro. Evokes nocifensive behavior in mice.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release.
Held et al.
Citation for CIM 0216
The citations listed below are publications that use Tocris products. Selected citations for CIM 0216 include:
1 Citation: Showing 1 - 1
Activation of gene transcription via CIM0216, a synthetic ligand of transient receptor potential melastatin-3 (TRPM3) channels.
Authors: Rubil and Thiel
Channels (Austin) 2017;11:79
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