Chemical Name: (3-Chlorophenyl) [3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]methanone
Biological ActivityCIQ is a subunit-selective potentiator of NMDA receptors containing the GluN2C (formally NR2C) or GluN2D (formally NR2D) subunit. Increases channel opening efficiency and enhances NMDA receptor responses.
Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors.
Mullasseril et al.
Citations for CIQ
The citations listed below are publications that use Tocris products. Selected citations for CIQ include:
2 Citations: Showing 1 - 2
Toll-like receptor 4 deficiency alters nucleus accumbens synaptic physiology and drug reward behavior.
Authors: Kashima and Grueter
Proc Natl Acad Sci U S A. 2017;114(33):8865
Molecular pharmacology of human NMDA receptors.
Authors: Hedegaard Et al.
Neurochem Int 2012;61:601
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