Catalog Number: 4105
Chemical Name: (3-Chlorophenyl) [3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]methanone
Biological Activity
Subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit. Increases channel opening efficiency and enhances NMDA receptor responses.
Technical Data
  • M.Wt:
    467.94
  • Formula:
    C26H26ClNO5
  • Solubility:
    Soluble to 100 mM in DMSO and to 10 mM in ethanol with sonication
  • Purity:
    >98%
  • Storage:
    Store at +4°C
  • CAS No:
    486427-17-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors.
    Mullasseril et al.
    Nat.Commun., 2010;1:1
Citations:

The citations listed below are publications that use Tocris products. Selected citations for CIQ include:

2 Citations: Showing 1 - 2
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  1. Toll-like receptor 4 deficiency alters nucleus accumbens synaptic physiology and drug reward behavior.
    Authors: Kashima and Grueter
    Proc Natl Acad Sci U S A. 2017;114(33):8865
  2. Molecular pharmacology of human NMDA receptors.
    Authors: Hedegaard Et al.
    Neurochem Int 2012;61:601

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