CIQ

Tocris Bioscience | Catalog # 4105

Potentiator of NMDA receptors containing GluN2C/GluN2D
Tocris Bioscience
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Key Product Details

Description

Potentiator of NMDA receptors containing GluN2C/GluN2D

Product Description

CIQ is a subunit-selective potentiator of NMDA receptors containing the GluN2C (formally NR2C) or GluN2D (formally NR2D) subunit. Increases channel opening efficiency and enhances NMDA receptor responses.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Product Specifications for CIQ

Molecular Weight

467.94

Formula

C26H26ClNO5

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(3-Chlorophenyl) [3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]methanone

CAS Number

486427-17-2

PubChem ID

4231127

InChI Key

VYMILMYEENZHAR-UHFFFAOYSA-N

SMILES

O=C(C3=CC(Cl)=CC=C3)N2C(COC4=CC=C(OC)C=C4)C1=CC(OC)=C(OC)C=C1CC2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 46.79 100

Preparing Stock Solutions for CIQ

The following data is based on the product molecular weight 467.94.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.14 mL 10.69 mL 21.37 mL
5 mM 0.43 mL 2.14 mL 4.27 mL
10 mM 0.21 mL 1.07 mL 2.14 mL
50 mM 0.04 mL 0.21 mL 0.43 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

Product Documents for CIQ

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CIQ

For research use only

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