Catalog Number: 0888
Chemical Name: 2-(2-Cyclopropylphenoxymethyl)imidazoline hydrochloride
Biological Activity
Selective α1 agonist. Also available as part of the α1-Adrenoceptor Tocriset™ and Mixed Adrenergic Tocriset™.
Technical Data
  • M.Wt:
    252.74
  • Formula:
    C13H16N2O.HCl
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    40600-13-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Binding of [3H]cirazoline to an imidazoline site in rat brain and kidney membranes.
    Le Rouzic et al.
    Eur.J.Pharmacol., 1995;278:261
  2. Renal effects of selective alpha-1 and alpha-2 adrenoreceptor agonists in conscious normotensive rats.
    Gellai and Ruffolo
    J.Pharmacol.Exp.Ther., 1987;240:723
  3. Further characterisation of the guinea pig cerebral cortex idazoxan receptor: solubilization, distinction from the imidazole site, and demonstration of cirazoline as an idazoxan receptor-selective drug.
    Wikberg and Uklen
    J.Neurochem., 1990;55:192
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Cirazoline hydrochloride include:

2 Citations: Showing 1 - 2
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  1. An Alpha-1A Adrenergic Receptor Agonist Prevents Acute Doxorubicin Cardiomyopathy in Male Mice.
    Authors: Montgomery
    Plos One 2017;12:e0168409
  2. Ectopic activity in the rat pulmonary vein can arise from simultaneous activation of alpha1- and beta1-adrenoceptors.
    Authors: Maupoil Et al.
    Br J Pharmacol 2007;150:899

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