Citalopram hydrobromide

Tocris Bioscience | Catalog # 1427

Highly potent and selective 5-HT uptake inhibitor
Tocris Bioscience

Key Product Details

Description

Highly potent and selective 5-HT uptake inhibitor
View all 5-HT Transporter Inhibitors »

Product Description

Citalopram hydrobromide is a highly selective and potent 5-HT uptake inhibitor with no effect on noradrenalin or dopamine uptake (IC50 values are 1.8, 8800 and 41000 nM respectively). Has negligible activity at a wide range of receptors.

Product Specifications for Citalopram hydrobromide

Molecular Weight

405.31

Formula

C20H21FN2O.HBr

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile hydrobromide

CAS Number

59729-32-7

PubChem ID

77995

InChI Key

WIHMBLDNRMIGDW-UHFFFAOYSA-N

SMILES

Br.CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 10
Ethanol 50

Preparing Stock Solutions for Citalopram hydrobromide

The following data is based on the product molecular weight 405.31.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.93 mL 24.67 mL 49.34 mL
2.5 mM 0.99 mL 4.93 mL 9.87 mL
5 mM 0.49 mL 2.47 mL 4.93 mL
25 mM 0.10 mL 0.49 mL 0.99 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 58 publications citing the usage of this product.

Product Documents for Citalopram hydrobromide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Citalopram hydrobromide

For research use only

Citations for Citalopram hydrobromide

Customer Reviews for Citalopram hydrobromide (2)

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  • Inhibition of Synaptic Transmission in the VP
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    Verified Customer | Posted 02/02/2020
    SERT blocker citalopram (1 μΜ)
    Citalopram hydrobromide 1427
  • Citalopram with cued fear conditioning
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    Verified Customer | Posted 05/23/2019
    dissolved in saline easily, given 60 min before behavior
    given before cued fear conditioning, 10mg/kg i.p. did not significantly affect freezing behavior during recall 24 hours later
    Citalopram hydrobromide 1427

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