Highly selective and potent 5-HT uptake inhibitor with no effect on noradrenalin or dopamine uptake (IC50
values are 1.8, 8800 and 41000 nM respectively). Has negligible activity at a wide range of receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Synthesis of S-[3-(4(5)-imidazolyl)propyl]-N-[2-(4-[125I]-iodophenylethyl]isothiourea sulfate [125I]-iodophenpropit), a new probe for histamine H3 receptor binding sites.
Menge et al.
J.Labelled Comp.Radiopharm. XXXI, 1992;10:781
Effect of chronic administration of the selective serotonin (5-HT) uptake inhibitor citalopram on extracellular 5-HT and apparent autoreceptor sensitivity in rat forebrain in vivo.
Auerbach and Hjorth
Naunyn Schmiedebergs Arch.Pharmacol., 1995;352:597
Inhibition of 5-hydroxytryptamine reuptake by the antidepressant citalopram in the locus coeruleus modulates the rat brain noradrenergic transmission in vivo.
Mateo et al.
The citations listed below are publications that use Tocris products. Selected citations for Citalopram hydrobromide include:
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