CK 666

Key Product Details

Product Description

CK 666 is an inhibitor of the Arp2/3 complex; inhibits actin polymerization (IC₅₀ = 4 μM).

Product Specifications for CK 666

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for CK 666

The following data is based on the product molecular weight 296.34.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.37 mL	16.87 mL	33.75 mL
5 mM	0.67 mL	3.37 mL	6.75 mL
10 mM	0.34 mL	1.69 mL	3.37 mL
50 mM	0.07 mL	0.34 mL	0.67 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 89 publications citing the usage of this product.

• Han and Nolen X-ray crystal structures and molecular mechanism of improved Arp2/3 complex inhibitors. 1751 ACSB 2009 Abstracts. American Society for Cel
• Nolen Characterization of two classes of small molecule inhibitors of Arp2/3 complex. Nature 2009 PMID: 19648907

Product Documents for CK 666