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CK 869

4984 2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4984/10
4984/50
Cat.No. 4984 - CK 869 | C17H16BrNO3S | CAS No. 388592-44-7
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Description: Arp2/3 inhibitor; inhibits actin polymerization
Alternative Names: CK-0157869

Chemical Name: 2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone

Purity: ≥98%

Product Details
Citations (2)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex. Inhibits actin polymerization (IC50= 11 μM). Does not inhibit budding or fission yeast Arp2/3 complexes.

Technical Data

M.Wt:
394.28
Formula:
C17H16BrNO3S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
388592-44-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Product Datasheets

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Citations for CK 869

The citations listed below are publications that use Tocris products. Selected citations for CK 869 include:

2 Citations: Showing 1 - 2

  1. Use of CK-548 and CK-869 as Arp2/3 complex inhibitors directly suppresses microtubule assembly both in vitro and in vivo.
    Authors: Yamagashi Et al.
    Biochem.Biophys.Res.Commun.  2018;496:834
  2. αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin.
    Authors: Bharadwaj
    Nat Commun  2017;8:14348

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