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CK 869

  ( 2 citations )    
Product Datasheet
Catalog Number:4984
Alternate Names:CK-0157869
Chemical Name:2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone
Product Details
Citations (2)
Reviews
Biological Activity
Inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex. Inhibits actin polymerization (IC50= 11 μM). Does not inhibit budding or fission yeast Arp2/3 complexes.
Technical Data
  • M.Wt:
    394.28
  • Formula:
    C17H16BrNO3S
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    388592-44-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for CK 869 include:

2 Citations: Showing 1 - 2
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  1. Use of CK-548 and CK-869 as Arp2/3 complex inhibitors directly suppresses microtubule assembly both in vitro and in vivo.
    Authors: Yamagashi Et al.
    Biochem.Biophys.Res.Commun.  2018;496:834
  2. αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin.
    Authors: Bharadwaj
    Nat Commun  2017;8:14348

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