Cl-4AS-1

Catalog # Availability Size / Price Qty
3812/10
3812/50
Cl-4AS-1 | CAS No. 188589-66-4 | Androgen Receptor Agonists
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Description: Steroidal androgen receptor agonist

Chemical Name: (4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)-N-(2-Chlorophenyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1,4,6a-trimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide

Purity: ≥99%

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Biological Activity

Potent steroidal androgen receptor agonist (IC50 = 12 nM). Mimics the action of 5α-dihydrotestosterone (DHT). Transactivates the mouse mammary tumor virus (MMTV) promoter; represses MMP1 promoter activity. Inhibits 5α-reductase type I and II (IC50 values are 6 and 10 nM respectively).

Technical Data

M.Wt:
441.01
Formula:
C26H33ClN2O2
Solubility:
Soluble to 10 mM in DMSO and to 10 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
188589-66-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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