Catalog Number: 2632
Chemical Name: N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide hydrochloride
Biological Activity
Selective inhibitor of MMP-13 (89% inhibition at 10 μg/mL) that displays no activity at MMP-1, MMP-9 or TACE. Inhibits in vitro invasion by the human pituitary adenoma cell line HP75.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water and to 75 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Structure-based design of a novel, potent, and selective inhibitor for MMP-13 utilizing NMR spectroscopy and computer-aided molecular design.
    Chen et al.
    J.Am.Chem.Soc., 2000;122:9648

The citations listed below are publications that use Tocris products. Selected citations for CL 82198 hydrochloride include:

Showing Results 1 - 1 of 1

  1. MMP13 is a critical target gene during the progression of osteoarthritis.
    Authors: Wang Et al.
    J Neurosci
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