CL 82198 hydrochloride

  ( 2 citations )    
Product Datasheet
Catalog Number:2632
Chemical Name:N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide hydrochloride
Product Details
Citations (2)
Reviews
Biological Activity
Selective inhibitor of MMP-13 (89% inhibition at 10 μg/mL) that displays no activity at MMP-1, MMP-9 or TACE. Inhibits in vitro invasion by the human pituitary adenoma cell line HP75. Rescues paclitaxel induced axon degradation and reduces associated neurotoxicity in zebrafish.
Technical Data
  • M.Wt:
    338.83
  • Formula:
    C17H23N2O3.HCl
  • Solubility:
    Soluble to 100 mM in water and to 75 mM in DMSO
  • Purity:
    >98
  • Storage:
    Desiccate at RT
  • CAS No:
    1188890-36-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for CL 82198 hydrochloride include:

2 Citations: Showing 1 - 2
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  1. MMP13 is a critical target gene during the progression of osteoarthritis.
    Authors: Wang Et al.
    J Neurosci  2013;15:R5
  2. MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation.
    Authors: Meierjohann Et al.
    Mol Cancer  2010;9:201

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