Chemical Name:N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide hydrochloride
Biological Activity Selective inhibitor of MMP-13 (89% inhibition at 10 μg/mL) that displays no activity at MMP-1, MMP-9 or TACE. Inhibits in vitro invasion by the human pituitary adenoma cell line HP75. Rescues paclitaxel induced axon degradation and reduces associated neurotoxicity in zebrafish.
Soluble to 100 mM in water and to 75 mM in DMSO
Desiccate at RT
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