Catalog Number: 4822
Chemical Name: Methyl-7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside hydrochloride
Biological Activity
Lincosamide antibiotic. Inhibits protein synthesis by binding to the 50S ribosomal subunit and preventing early peptide chain elongation in bacteria.
Technical Data
  • M.Wt:
    461.44
  • Formula:
    C18H33ClN2O5S.HCl
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    21462-39-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.
Background References
  1. Specific inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells by 16-membered macrolide, lincosamide, and streptogramin B antibiotics.
    Champney and Tober
    Curr.Microbiol., 2000;41:126
  2. Clindamycin: a review of fifteen years of experience.
    Dhawan and Thadepalli
    Rev.Infect.Dis., 1982;4:1133

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