Chemical Name: Methyl-7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside hydrochloride
Biological ActivityLincosamide antibiotic. Inhibits protein synthesis by binding to the 50S ribosomal subunit and preventing early peptide chain elongation in bacteria.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Specific inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells by 16-membered macrolide, lincosamide, and streptogramin B antibiotics.
Champney and Tober
Clindamycin: a review of fifteen years of experience.
Dhawan and Thadepalli
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Clindamycin and Vancomycin combination therapy was studied. Susceptibility and time kill studies were carried out on MRSA.