Clindamycin hydrochloride

Tocris Bioscience | Catalog # 4822

Antibiotic; inhibits protein synthesis
Tocris Bioscience
Discontinued Product
4822 has been discontinued. View all Antibiotics products.

Key Product Details

Description

Antibiotic; inhibits protein synthesis
View all Antibiotics »

Product Description

Clindamycin hydrochloride is a lincosamide antibiotic. Inhibits protein synthesis by binding to the 50S ribosomal subunit and preventing early peptide chain elongation in bacteria.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Product Specifications for Clindamycin hydrochloride

Molecular Weight

461.44

Formula

C18H33ClN2O5S.HCl

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

Methyl-7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside hydrochloride

CAS Number

21462-39-5

PubChem ID

16051951

InChI Key

AUODDLQVRAJAJM-XJQDNNTCSA-N

SMILES

CN1[C@H]([C@@](N[C@@]([H])([C@@]2([H])O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](Cl)C)=O)C[C@@H](CCC)C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 46.14 100

Preparing Stock Solutions for Clindamycin hydrochloride

The following data is based on the product molecular weight 461.44.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.17 mL 10.84 mL 21.67 mL
5 mM 0.43 mL 2.17 mL 4.33 mL
10 mM 0.22 mL 1.08 mL 2.17 mL
50 mM 0.04 mL 0.22 mL 0.43 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Clindamycin hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Clindamycin hydrochloride

For research use only

Customer Reviews for Clindamycin hydrochloride (1)

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  • Clindamycin and Vancomycin combination therapy study
    Name: Richard Whiteoak
    Species: MRSA
    Assay Type: In Vitro
    Verified Customer | Posted 11/13/2018
    Clindamycin and Vancomycin combination therapy was studied. Susceptibility and time kill studies were carried out on MRSA.
    Clindamycin hydrochloride 4822

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