CMA

Key Product Details

Product Description

CMA is a STING agonist; murine-selective (K_d = 3.5 μM). Triggers type I IFN response in murine macrophages, with no effect on human STING signaling.

Product Specifications for CMA

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for CMA

The following data is based on the product molecular weight 253.25.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.95 mL	19.74 mL	39.49 mL
5 mM	0.79 mL	3.95 mL	7.90 mL
10 mM	0.39 mL	1.97 mL	3.95 mL
50 mM	0.08 mL	0.39 mL	0.79 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Cavlar Species-specific detection of the antiviral small-molecule compound CMA by STING. EMBO J. 2013 PMID: 23604073
• Zhang Rat and human STINGs profile similarly towards anticancer/antiviral compounds. Sci. Rep. 2015 PMID: 26669264
• Haag Targeting STING with covalent small-molecule inhibitors. Nature 2018 PMID: 29973723

Product Documents for CMA