Chemical Name: 9-Oxo-10(9H)-acridineacetic acid
Biological ActivityMurine-selective STING agonist (Kd = 3.5 μM); triggers type I IFN response in murine macrophages. However, does not activate human STING signaling.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Rat and human STINGs profile similarly towards anticancer/antiviral compounds.
Zhang et al.
Targeting STING with covalent small-molecule inhibitors.
Haag et al.
Species-specific detection of the antiviral small-molecule compound CMA by STING.
Cavlar et al.
EMBO J., 2013;32:1440
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