Catalog Number: 4756
Chemical Name: N-(Adamant-1-yl)-4-oxo-1-pentyl-6-phenyl-1,4-dihydroquinoline-3-carboxamide
Biological Activity
Selective inverse agonist of CB2 receptors (Ki values are 3.8 and >10,000 nM for CB2 and CB1, respectively).
Technical Data
  • M.Wt:
    468.63
  • Formula:
    C31H36N2O2
  • Solubility:
    Soluble to 100 mM in ethanol and to 20 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    1048039-15-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo.
    Pasquini et al.
    J.Med.Chem., 2008;51:5075
  2. A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury.
    Contartese
    Pharmacol.Res., 2012;66:555

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