CP 690550 citrate

Catalog # Availability Size / Price Qty
4556/10
4556/50
Cat.No. 4556 - CP 690550 citrate | C16H20N6O.C6H8O7 | CAS No. 540737-29-9
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Description: Potent JAK inhibitor
Alternative Names: Tofacitinib citrate

Chemical Name: (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile citrate

Product Details
Citations (2)
Reviews

Biological Activity

Potent JAK inhibitor (IC50 values are 1, 20, and 112 nM for JAK3, JAK2 and JAK1 respectively). Orally active immunosuppressant; exhibits efficacy in rodent rheumatoid arthritis models.

External Portal Information

Chemicalprobes.org is a portal that offers independent guidance on the selection and/or application of small molecules for research. The use of CP 690550 (Tofacitinib) is reviewed on the chemical probes website.

Technical Data

Formula:
C16H20N6O.C6H8O7
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
CAS No:
540737-29-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Product Datasheets

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Reconstitution Calculator

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Citations for CP 690550 citrate

The citations listed below are publications that use Tocris products. Selected citations for CP 690550 citrate include:

2 Citations: Showing 1 - 2

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