CP 809101 hydrochloride

Key Product Details

Product Description

CP 809101 hydrochloride is a potent and selective 5-HT_2C receptor agonist (pEC₅₀ values are 9.96, 7.19 and 6.81 for human 5-HT_2C, 5-HT_2B and 5-HT_2A receptors respectively). Displays antipsychotic activity; suppresses condition avoidance responding (CAR) and inhibits PCP and amphetamine-stimulated hyperactivity in rats following subcutaneous administration.

Product Specifications for CP 809101 hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for CP 809101 hydrochloride

The following data is based on the product molecular weight 341.24.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.93 mL	14.65 mL	29.30 mL
5 mM	0.59 mL	2.93 mL	5.86 mL
10 mM	0.29 mL	1.47 mL	2.93 mL
50 mM	0.06 mL	0.29 mL	0.59 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

• Kalgutkar Genotoxicity of 2-(3-chlorobenzyloxy)-6-(piperazinyl)pyrazine, a novel 5-hydroxytryptamine_2c receptor agonist for the treatment of obesity: role of metabolic activation. Drug Metab.Dispos. 2007 PMID: 17344339
• Jensen Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT2A/5-HT2C receptor agonists with pro-cognitive J.Med.Chem 2013 PMID: 23301527
• Siuciak CP-809,101, a selective 5-HT_2C agonist, shows activity in animal models of antipsychotic activity. Neuropharmacology 2007 PMID: 16949622

Product Documents for CP 809101 hydrochloride