Biological Activity DOCK2-Rac1 interaction inhibitor; suppresses DOCK2-induced Rac1 activation. Also inhibits DOCK1 and DOCK5. Exhibits selectivity over DOCK9. Reduces chemotactic responses in vitro and in vivo, and activates T cells in vitro. Also attenuates HER2-mediated breast cancer cell migration in vitro.
Soluble to 50 mM in DMSO
Store at -20°C
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