CRBN5-SNAP2-1C-PIP
Chemical Name: N-(4-(((2-Amino-6-chloropyrimidin-4-yl)oxy)methyl)benzyl)-2-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperidin-4-yl)acetamide
Purity: ≥97%
Biological Activity
CRBN5-SNAP2-1C-PIP is a Degrader (PROTAC®) of SNAP-tag™ labeled fusion proteins (Dmax = 75% at 1 μM). CRBN5-SNAP2-1C-PIP recruits cereblon E3 ligase to induce the degradation of SNAP-fusion proteins.PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
SNAP-tag is a trademark of New England BioLabs, Inc.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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