CRBN5-SNAP2-1C-PIP

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CRBN5-SNAP2-1C-PIP | Active Degraders
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Description: Degrader (PROTAC®) of SNAP-tag™ labeled fusion proteins

Chemical Name: N-(4-(((2-Amino-6-chloropyrimidin-4-yl)oxy)methyl)benzyl)-2-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperidin-4-yl)acetamide

Purity: ≥97%

Product Details
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Biological Activity

CRBN5-SNAP2-1C-PIP is a Degrader (PROTAC®) of SNAP-tag™ labeled fusion proteins (Dmax = 75% at 1 μM). CRBN5-SNAP2-1C-PIP recruits cereblon E3 ligase to induce the degradation of SNAP-fusion proteins.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

SNAP-tag is a trademark of New England BioLabs, Inc.

Technical Data

M.Wt:
646.1
Formula:
C32H32ClN7O6
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥97%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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