CRT 0066854 hydrochloride

Catalog # Availability Size / Price Qty
5922/10
5922/50
CRT 0066854 hydrochloride | CAS No. 2250019-91-9 | Protein Kinase C Inhibitors
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Description: PKCι and PKCζ inhibitor

Chemical Name: (2S)-3-Phenyl-N1-[5,6,7,8-tetrahydro-2-(4-pyridinyl)[1]benzothieno[2,3-d]pyrimidin-4-yl]-1,2-propanediamine dihydrochloride

Purity: ≥98%

Product Details
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Biological Activity

CRT 0066854 hydrochloride is a protein kinase C (PKC) inhibitor. Inhibits PKCι and PKCζ (IC50 values are 132 and 639 nM, respectively). Restores polarized morphogenesis in oncogene expressing MDCK cells, decreases colony formation in HeLa cells and inhibits lethal giant larvae 2 (LLGL2) phosphorylation.

Technical Data

M.Wt:
488.48
Formula:
C24H25N5S.2HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2250019-91-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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