CRT 0105950

Catalog # Availability Size / Price Qty
6273/10
Cat.No. 6273 - CRT 0105950 | C21H16ClN3OS | CAS No. 1661845-86-8
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Description: Potent LIMK1/2 inhibitor

Chemical Name: 4-[[5-[3-(2-Chloro-4-methylphenyl)-4-pyridinyl]-2-thiazolyl]amino]phenol

Purity: ≥98%

Product Details
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Biological Activity

Potent LIMK1/2 inhibitor (IC50 values are 0.3 and 1 nM at LIMK 1 and 2, respectively). Disrupts microtubule organization, inhibits cofilin phosphorylation and increases α-tubulin acetylation in vitro.

Technical Data

M.Wt:
393.89
Formula:
C21H16ClN3OS
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1661845-86-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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