CRT 0105950

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CRT 0105950 | CAS No. 1661845-86-8 | LIMK Inhibitors
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Description: Potent LIMK1/2 inhibitor

Chemical Name: 4-[[5-[3-(2-Chloro-4-methylphenyl)-4-pyridinyl]-2-thiazolyl]amino]phenol

Purity: ≥98%

Product Details

Biological Activity

CRT 0105950 is a potent LIMK1/2 inhibitor (IC50 values are 0.3 and 1 nM at LIMK 1 and 2, respectively). Disrupts microtubule organization, inhibits cofilin phosphorylation and increases α-tubulin acetylation in vitro.

Technical Data

Soluble to 100 mM in DMSO and to 50 mM in ethanol
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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