CU CPT 22

  ( 1 citations )    
Product Datasheet
Catalog Number:4884
Chemical Name:3,4,6-Trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylic acid hexyl ester
Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity
Selective toll-like receptor 1/2 (TLR1/2) inhibitor (IC50 = 0.58 μM). Exhibits no activity at TLR2/TLR6, TLR3, TLR4 and TLR7 or a panel of 10 representative kinases. Inhibits the release of proinflammatory cytokines TNF-α and IL-1β.
Technical Data
  • M.Wt:
    362.37
  • Formula:
    C19H22O7
  • Solubility:
    Soluble to 100 mM in DMSO and to 50 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    1416324-85-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under license from the University of Colorado
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for CU CPT 22 include:

1 Citations: Showing 1 - 1

  1. Inflammasome priming is similar for francisella species that differentially induce inflammasome activation.
    Authors: Ghonime Et al.
    Nucleic Acids Res  2015;10:e0127278

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