CVT 313

   
Product Datasheet
Catalog Number:6174
Chemical Name:2,2'-[[6-[[(4-Methoxyphenyl)methyl]amino]-9-(1-methylethyl)-9H-purin-2-yl]imino]bis[ethanol]
Product Details
Reviews
Biological Activity
cdk2 inhibitor (IC50 = 0.5 μM). Exhibits >8-fold selectivity for CDK2 over CDK1 and CDK4 (IC50 values are 4.2 and 215 μM, respectively). Inhibits proliferation rat neonatal aortic smooth muscle cells and a range of tumor cells lines in vitro. Inhibits restenosis in a rat carotid artery injury model.
Technical Data
  • M.Wt:
    400.47
  • Formula:
    C20H28N6O3
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    199986-75-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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