CX08005

Catalog # Availability Size / Price Qty
6144/25
6144/5
Cat.No. 6144 - CX08005 | C28H39NO4 | CAS No. 1256341-22-6
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Description: Competitive PTP1B inhibitor

Chemical Name: 2-[[[2-(Tetradecyl)phenyl]amino]carbonyl]benzoic acid

Purity: ≥98%

Product Details
Reviews

Biological Activity

Competitive PTP1B inhibitor (IC50 = 0.781 μM). Binds catalytic P-loop of enzyme. Improves insulin sensitivity in obese mice in the glucose tolerance test and the homeostasis model assessment of insulin resistance index (HOMA-IR). Enhances insulin-induced glucose uptake in adipocytes and myotubes in vitro. Exhibits some selectivity for PTP1B over other protein tyrosine phosphatases, except TCPTP.

Technical Data

M.Wt:
453.61
Formula:
C28H39N04
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1256341-22-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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