CycLuc 1
Chemical Name: (4S)-2-(6,7-Dihydro-5H-pyrrolo[3,2-f]benzothiazol-2-yl)-4,5-dihydro-4-thiazolecarboxylic acid
Purity: ≥98%
Biological Activity
CycLuc 1 is a synthetic luciferase substrate. Displays near-infrared (NIR) emission; peak luminescence at 599 nm. Suitable for use in in vivo bioluminescence imaging. Brain penetrant.Optical Data for CycLuc 1
| Emission Color | Orange |
|---|---|
| λem | 600 nm |
| Cell Permeable | Yes |
| Application | In vivo bioluminescence imaging BLI |
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Robust light emission from cyclic alkylaminoluciferin substrates for firefly luciferase.
Reddy et al.
J.Am.Chem.Soc., 2010;132:13586 -
A synthetic luciferin improves bioluminescence imaging in live mice.
Evans et al.
Nat.Methods., 2014;11:393
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