Chemical Name: 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidine)-methylpiperidine hydrochloride
Biological Activity Non-selective 5HT2 antagonist, migraine prophylactic. Also SETD7/9 inhibitor (IC50 = 1μM). Decreases expression and increases degradation of estrogen receptor (ER) α in breast tumor MCF7 cells. Inhibits growth of MCF7 xenografts in mice.
Soluble to 100 mM in DMSO
Store at RT
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