Cyproheptadine hydrochloride

  ( 2 citations )    
Product Datasheet
Catalog Number:0996
Chemical Name:4-(5H-Dibenzo[a,d]cyclohepten-5-ylidine)-methylpiperidine hydrochloride
Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity
Non-selective 5HT2 antagonist, migraine prophylactic. Also SETD7/9 inhibitor (IC50 = 1μM). Decreases expression and increases degradation of estrogen receptor (ER) α in breast tumor MCF7 cells. Inhibits growth of MCF7 xenografts in mice.
Technical Data
  • M.Wt:
    323.86
  • Formula:
    C21H21N.HCl
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    969-33-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Cyproheptadine hydrochloride include:

2 Citations: Showing 1 - 2
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  1. Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors.
    Authors: Murray Et al.
    Nat Med  2010;16:694
  2. Locomotion after spinal cord injury depends on constitutive activity in serotonin receptors.
    Authors: Fouad Et al.
    J Neurophysiol  2010;104:2975

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