Cyproheptadine hydrochloride

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin).
   Hoyer et al.
   Pharmacol.Rev., 1994;46:157
3. Inhibitory 5-hydroxytryptamine receptors involved in pressor effects obtained by stimulation of sympathetic outflow from spinal cord in pithed rats.
   Moran et al.
   Br.J.Pharmacol., 1994;113:1358
4. Identification of cyprohept. as an inhibitor of SET domain containing lysine methyltransferase 7/9 (Set7/9) that regulates estrogen-dependent transcription.
   Takemoto et al.
   J.Med.Chem., 2016;59:3650

Product Datasheets