Cys-T7 Peptide
Tocris Bioscience | Catalog # 8904
Targeting peptide for the transferrin receptor (N-term Cys)
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Key Product Details
Description
Targeting peptide for the transferrin receptor (N-term Cys)
Product Description
Cys-T7 Peptide is a targeting peptide for the transferrin receptor (N-term Cys), a protein abundantly expressed on endothelial cells, including those forming the blood-brain barrier (BBB). Cys-T7 Peptide facilitates receptor-mediated endocytosis and transcytosis, making it an ideal targeting agent for drug delivery systems, such as lipid nanoparticles (LNPs), across biological barriers. N-term cys residue enables thiol-maleimide-based conjugation to DSPE-PEG 2000 Maleimide (Cat. No. 7947) commonly used to synthesize LNPs.
Product Specifications for Cys-T7 Peptide
Molecular Weight
996.15
Formula
C44H65N15O10S
Storage
Store at -20°C
Purity
≥95% (HPLC)
InChI Key
SMAWGRDHSYDHOY-WBLMYSKVSA-N
SMILES
O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CC=C(C=C2)O)C(N3[C@@H](CCC3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC4=CNC=N4)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CS)N
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 2mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product.
- Han Peptide-functionalized lipid nanoparticles for targeted systemic mRNA delivery to the brain. Nano Lett. 2025 PMID: 39688915
- Han Plasmid pORF-hTRAIL and doxorubicin co-delivery targeting to tumor using peptide-conjugated polyamidoamine dendrimer. Biomaterials 2011 PMID: 20971503
Product Documents for Cys-T7 Peptide
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Cys-T7 Peptide
For research use only
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