Cytosporone B

   
Product Datasheet
Catalog Number:5459
Chemical Name:Ethyl 3,5-dihydroxy-2-(1-oxooctyl)-benzeneacetate
Product Details
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Biological Activity
Naturally occurring Nur77 (NR4A1) agonist (Kd = 8.52 x 10-7 M). Induces apoptosis in gastric cancer cells in vitro. Increases blood glucose levels in fasting C57 mice and suppresses xenograft tumor growth. Also exhibits a potent antifibrotic effect in bleomycin-induced skin fibrosis in vivo.
Technical Data
  • M.Wt:
    322.4
  • Formula:
    C18H26O5
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    321661-62-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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