Chemical Name: Ethyl 3,5-dihydroxy-2-(1-oxooctyl)-benzeneacetate
Biological ActivityCytosporone B is a naturally occurring Nur77 (NR4A1) agonist (Kd = 8.52 x 10-7 M). Induces apoptosis in gastric cancer cells in vitro. Increases blood glucose levels in fasting C57 mice and suppresses xenograft tumor growth. Also exhibits a potent antifibrotic effect in bleomycin-induced skin fibrosis in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Cytosporone B is an agonist for nuclear orphan receptor Nur77.
Zhan et al.
Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis.
Palumbo-Zerr et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for Cytosporone B
There are currently no reviews for this product. Be the first to review Cytosporone B and earn rewards!
Have you used Cytosporone B?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image