Cytosporone B

Catalog # Availability Size / Price Qty
5459/10
5459/50
Cat.No. 5459 - Cytosporone B | C18H26O5 | CAS No. 321661-62-5
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Description: High affinity Nur77 agonist

Chemical Name: Ethyl 3,5-dihydroxy-2-(1-oxooctyl)-benzeneacetate

Purity: ≥98%

Product Details
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Biological Activity

Naturally occurring Nur77 (NR4A1) agonist (Kd = 8.52 x 10-7 M). Induces apoptosis in gastric cancer cells in vitro. Increases blood glucose levels in fasting C57 mice and suppresses xenograft tumor growth. Also exhibits a potent antifibrotic effect in bleomycin-induced skin fibrosis in vivo.

Technical Data

M.Wt:
322.4
Formula:
C18H26O5
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
321661-62-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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