Catalog Number: 2813
Alternate Names: Dextroamphetamine sulfate
Chemical Name: (+)-α-Methylphenethylamine hemisulfate salt
Biological Activity
CNS stimulant. Targets monoamine transporters to elevate synaptic levels of noradrenalin, dopamine and serotonin.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
  • Storage:
    Desiccate at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Effects of withdrawal from an escalating dose schedule of d-Amphetamine on sexual behavior in the male rat.
    Barr et al.
    Pharmacol.Biochem.Behav., 1999;64:597
  2. The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-Amphetamine motor behaviors in rats.
    Cartmell et al.
    J.Pharmacol.Exp.Ther., 1999;291:161
  3. Balance between dopamine and serotonin release modulates behavioral effects of Amphetamine-type drugs.
    Rothman and Baumann
    Ann.N.Y.Acad.Sci., 2006;1074:245

The citations listed below are publications that use Tocris products. Selected citations for D-Amphetamine sulfate include:

3 Citations: Showing 1 - 3
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  1. Lateral diffusion of Gαs in the plasma membrane is decreased after chronic but not acute antidepressant treatment: role of lipid raft and non-raft membrane microdomains.
    Authors: Czysz Et al.
    PLoS One 2015;40:766
  2. Metabotropic glutamate receptor 5 knockout promotes motor and biochemical alterations in a mouse model of Huntington's disease.
    Authors: Ribeiro Et al.
    Neuropsychopharmacology 2014;23:2030
  3. DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1.
    Authors: Soda Et al.
    Mol Psychiatry 2013;18:898

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