Biological ActivitySelective vasopressin V1B receptor agonist (Ki values are 0.16, 64, 100 and 3800 nM for V1B, oxytocin, V2 and V1A receptors respectively). Displays weak antidiuretic, vasopressor and in vitro oxytocic activities.
(Modifications: X = Mpr, Gly-9 = C-terminal amide, Disulfide bridge between X-1 - Cys-6)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Design and synthesis of the frist selective agonists for the rat vasopressin V1b receptor: based on modifications of deamino-[cys1]arginine vasopressin at positions 4 and 8.
Pena et al.
Pharmacological and physiological characterization of d[Leu4,Lys8]vasopressin, the first V1b-selective agonist for rat vasopressin/oxytocin receptors.
Pena et al.
Citation for d[Leu4,Lys8]-VP
The citations listed below are publications that use Tocris products. Selected citations for d[Leu4,Lys8]-VP include:
1 Citation: Showing 1 - 1
A circuit from hippocampal CA2 to lateral septum disinhibits social aggression.
Authors: Leroy Et al.
No product specific FAQs exist for this product, however you mayView all Peptide FAQs
VersaClone cDNA Plasmids
Reviews for d[Leu4,Lys8]-VP
There are currently no reviews for this product. Be the first to review d[Leu4,Lys8]-VP and earn rewards!
Have you used d[Leu4,Lys8]-VP?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image