Catalog Number: 1884
Alternate Names: GPAnt-2 analog
Biological Activity
Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Trp-7, Trp-9, Trp-10 = D-Trp, Met-11 = C-terminal Amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding.
    Mukai et al.
    J.Biol.Chem., 1992;267:16237

The citations listed below are publications that use Tocris products. Selected citations for [D-Trp7,9,10]-Substance P include:

Showing Results 1 - 1 of 1

  1. Microtubule dynamics at the growth cone are mediated by α7 nicotinic receptor activation of a Gαq and IP3 receptor pathway.
    Authors: Nordman and Kabbani
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