Substance P analog that inhibits activation of Gq/11
muscarinic ACh receptors. Does not inhibit Gi/o
activation by M2
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G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding.
Mukai et al.
The citations listed below are publications that use Tocris products. Selected citations for [D-Trp7,9,10]-Substance P include:
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