DADLE

Name: DADLE
Brand: Tocris Bioscience
SKU: 3790

Tocris Bioscience | Catalog # 3790

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Citations (11)

Product Documents

Prototypical δ agonist

Discontinued Product

3790 has been discontinued. View all delta Opioid Receptor Agonists products.

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Prototypical δ agonist

Alternative Names

[D-Ala²,D-Leu⁵]-Enkephalin

View all delta Opioid Receptor Agonists »

Product Description

DADLE is a prototypical δ-opioid receptor agonist that also displays activity at the μ-opioid receptor. Displays antinociceptive activity in vivo.

Product Specifications for DADLE

Molecular Weight

569.66

Formula

C₂₉H₃₉N₅O₇

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

63631-40-3

PubChem ID

6917707

InChI Key

ZHUJMSMQIPIPTF-IBURTVSXSA-N

SMILES

[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

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g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Concentration 2 (C2)

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The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 11 publications citing the usage of this product.

Ke Delta opioid agonist [D-Ala², D-Leu⁵] enkephalin (DADLE) reduced oxygen-glucose deprivation caused neuronal injury through the MAPK pathway. Brain Res. 2009 PMID: 19619518
Suh and Tseng Different types of opioid receptors mediating analgesia induced by morphine, DAMGO, DPDPE, DADLE and beta-endorphin in mice. Naunyn-Schmied.Arch.Pharmacol.
Mulder Pharmacological profile of various κ-agonists at κ-, μ- and δ-opioid receptors mediating presynaptic inhibition of neurotransmitter release in the rat brain. Br.J.Pharmacol. 1991 PMID: 1673074

Product Documents for DADLE

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for DADLE

For research use only

Citations for DADLE

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