DAU 5884 hydrochloride

Key Product Details

Product Description

DAU 5884 hydrochloride is a selective muscarinic M₃ receptor antagonist. In bovine tracheal smooth muscle, inhibits methacholine-dependent effects on cell proliferation and muscle contractility.

Product Specifications for DAU 5884 hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for DAU 5884 hydrochloride

The following data is based on the product molecular weight 351.83.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.84 mL	14.21 mL	28.42 mL
5 mM	0.57 mL	2.84 mL	5.68 mL
10 mM	0.28 mL	1.42 mL	2.84 mL
50 mM	0.06 mL	0.28 mL	0.57 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Gosens Muscarinic M₃ receptor-dependent regulation of airway smooth muscle contractile phenotype. Br.J.Pharmacol. 2004 PMID: 14993104
• Roffel Cholinergic contraction of the guinea pig lung strip is mediated by muscarinic M₂-like receptors. Eur.J.Pharmacol. 1993 PMID: 8112384
• Gosens Muscarinic M₃-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle. Am.J.Respir.Cell Mol.Biol. 2003 PMID: 12540494
• Doods Characterization of muscarinic receptors in guinea-pig uterus. Eur.J.Pharmacol. 1993 PMID: 8112383

Product Documents for DAU 5884 hydrochloride