DDR1 Antibody (51D6) - BSA Free

Novus Biologicals | Catalog # NBP3-09168

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgM Clone # 51D6

Format

BSA Free
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Product Specifications

Immunogen

DDR1-transfected NIH-3T3 cells

Specificity

The mouse monoclonal antibody 51D6 recognizes an extracellular epitope of CD167a, an approximately 97-101 kDa receptor tyrosine kinase expressed mainly on epithelial cells, but also on B cells and dendritic cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgM

Scientific Data Images for DDR1 Antibody (51D6) - BSA Free

Flow Cytometry: DDR1 Antibody (51D6) [NBP3-09168]

Flow Cytometry: DDR1 Antibody (51D6) [NBP3-09168]

Flow Cytometry: DDR1 Antibody (51D6) [NBP3-09168] - Analysis (surface staining) of MCF-7 cell line stained with anti-human CD167a (51D6) purified, GAM-APC (red) in comparison with FMO (fluorescence minus one) sample (black-dashed).

Applications for DDR1 Antibody (51D6) - BSA Free

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Chromatography

Formulation

Tris buffered saline (TBS), pH 8.0

Format

BSA Free

Preservative

15mM Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: DDR1

Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. This gene is located on chromosome 6p21.3 in proximity to several HLA class I genes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]

Long Name

Discoidin Domain Receptor 1

Alternate Names

CAK, CD167a, RTK6, TrkE

Gene Symbol

DDR1

Additional DDR1 Products

Product Documents for DDR1 Antibody (51D6) - BSA Free

Certificate of Analysis

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Product Specific Notices for DDR1 Antibody (51D6) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for DDR1 Antibody (51D6) - BSA Free

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  • Q: I was wondering if you offer, or are planning on offering, any antibodies targeted to specific phosphorylation sites on the receptor tyrosine kinase DDR1.

    A: At this time we do not offer and DDR1 antibodies specific for certain phosphorylation states.

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