Delavirdine mesylate

Catalog # Availability Size / Price Qty
4149/10
4149/50
Delavirdine mesylate | CAS No. 147221-93-0 | RNA/DNA Polymerase Inhibitors
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Description: Non-nucleoside reverse transcriptase inhibitor
Alternative Names: U 90152

Chemical Name: 1-[3-[(1-Methylethyl)amino]-2-pyridinyl]-4-[[5-[(methylsulfonyl)amino]-1H-indol-2-yl]carbonyl]-piperazine monomethanesulfonate

Purity: ≥99%

Product Details
Reviews

Biological Activity

Non-nucleoside reverse transcriptase inhibitor (NNRTI). Selectively inhibits HIV-1 reverse transcriptase (RNA-dependent DNA polymerase) over other cellular polymerases (IC50 values are 0.26, 440 and >550 μM for HIV-1 reverse transcriptase, DNA polymerase α and DNA polymerase δ). Prevents HIV-1 spread in vivo and blocks viral replication in peripheral blood lymphocytes. Orally active.

Technical Data

M.Wt:
552.67
Formula:
C22H28N6O3S.CH3SO3H
Solubility:
Soluble to 75 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
147221-93-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Viiv.

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