Deoxynivalenol

Catalog # Availability Size / Price Qty
3976/1
Miscellaneous Compounds Small Molecule
1 Image
Description: Mycotoxin; potent protein synthesis inhibitor
Alternative Names: DON, Vomitoxin

Chemical Name: 3α,7α,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-one

Product Details
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Biological Activity

Tricothecene mycotoxin and potent protein synthesis inhibitor. Exhibits cytotoxic activity in vivo via the ribotoxic stress response. Induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-κB into the nucleus.

Technical Data

M.Wt:
296.32
Formula:
C15H20O6
Solubility:
Soluble to 30 mM in ethanol
Storage:
Store at +4°C
CAS No:
51481-10-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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