Dexamethasone

  ( 3 citations )    
Product Datasheet
Catalog Number:1126
Chemical Name:(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione
Product Details
Citations (3)
Reviews
Biological Activity
Glucocorticoid; anti-inflammatory. Reduces levels of activated NF-κB in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. Induces differentiation of human mesenchymal stem cells (MSCs). Also induces autophagy in acute lymphoblastic leukemia (ALL) cell lines.
Technical Data
  • M.Wt:
    392.47
  • Formula:
    C22H29FO5
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    50-02-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Dexamethasone include:

3 Citations: Showing 1 - 3
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  1. Synergistic Anti-Tumor Activity of EZH2 Inhibitors and Glucocorticoid Receptor Agonists in Models of Germinal Center Non-Hodgkin Lymphomas.
    Authors: Knutson Et al.
    PLoS One  2014;9:e111840
  2. The human tissue-biomaterial interface: a role for PPARγ-dependent glucocorticoid receptor activation in regulating the CD163+ M2 macrophage phenotype.
    Authors: Bullers Et al.
    Tissue Eng Part A  2014;20:2390
  3. Riluzole elevates GLT-1 activity and levels in striatal astrocytes.
    Authors: Carbone Et al.
    J Neurosci  2012;60:42613

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