DH 97

Key Product Details

Product Description

DH 97 is a relatively potent MT₂ melatonin receptor antagonist (pK_i value = 8.03), displaying 89- and 229-fold selectivity over MT₁ and GPR50 (melatonin-related orphan receptor) respectively.

Product Specifications for DH 97

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for DH 97

The following data is based on the product molecular weight 334.46.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.99 mL	14.95 mL	29.90 mL
5 mM	0.60 mL	2.99 mL	5.98 mL
10 mM	0.30 mL	1.49 mL	2.99 mL
50 mM	0.06 mL	0.30 mL	0.60 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

• Ting Molecular and pharmacological evidence for MT₁ melatonin receptor subtype in the tail artery of juvenile Wistar rats. Br.J.Pharmacol. 1999 PMID: 10433507
• Teh and Sugden Comparison of the relationships of melatonin receptor agonists and antagonists; lengthening the N-acyl side chain has differing effects on potency on Xenopus melanophores. Naunyn Schmiedebergs Arch.Pharmacol. 1998 PMID: 9840420

Product Documents for DH 97