A relatively potent MT2
melatonin receptor antagonist (pKi
value = 8.03), displaying 89- and 229-fold selectivity over MT1
and GPR50 (melatonin-related orphan receptor) respectively.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Molecular and pharmacological evidence for MT1 melatonin receptor subtype in the tail artery of juvenile Wistar rats.
Ting et al.
Comparison of the relationships of melatonin receptor agonists and antagonists; lengthening the N-acyl side chain has differing effects on potency on Xenopus melanophores.
Teh and Sugden
Naunyn Schmiedebergs Arch.Pharmacol., 1998;358:522
The citations listed below are publications that use Tocris products. Selected citations for DH 97 include:
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