Dibutyryl-cAMP, sodium salt

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Dibutyryl-cAMP, sodium salt | CAS No. 16980-89-5 | cAMP Compounds
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Description: Cell-permeable cAMP analog

Chemical Name: N6,O2'-Dibutyryl adenosine 3',5'-cyclic monophosphate sodium salt

Purity: ≥98%

Product Details
Citations (4)

Biological Activity

Dibutyryl-cAMP sodium salt is a cell-permeable analog of cAMP that activates cAMP-dependent protein kinases and is a phosphodiesterase inhibitor. Combined with other reagents, dibutyryl-cAMP promotes differentiation of neural stem/progenitor cells (NSPCs) and other cell lines and increases survival rates of NSPCs and differentiation into neurons in vivo. Promotes neurite outgrowth in cell cultures. Dibutyryl-cAMP has anti-inflammatory activity and is used to promote wound healing. Choline acetyltransferase and vesicular acetylcholine transporter mRNA are increased in cells treated with dibutyryl-cAMP.

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Dibutyryl-cAMP, sodium salt

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