Dihydroergotoxine mesylate

   
Product Datasheet
Catalog Number:0505
Chemical Name:
Product Details
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Biological Activity
A complex of closely related alkaloid salts. Binds with high affinity to the GABAA receptor Cl- channel, producing an allosteric interaction with the benzodiazepine site. Also interacts with central dopaminergic, serotonergic and adrenergic (α1) receptors. Displays antiproliferative activity in vitro (IC50 = 18 - 38 μM in prostate cancer cells) and exhibits cognition-enhancing, anticonvulsant and sedative activity in vivo. Orally active.
Technical Data
  • Solubility:
    Soluble in ethanol
  • Storage:
    Store at RT
  • CAS No:
    8067-24-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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