Dipyridamole

Tocris Bioscience | Catalog # 0691

Adenosine transport inhibitor
Tocris Bioscience

Key Product Details

Description

Adenosine transport inhibitor
View all Nucleoside Transporter Inhibitors »

Product Description

Dipyridamole is a coronary vasodilator; adenosine transport inhibitor. Phosphodiesterase inhibitor (IC50 values are 0.37, 0.38, 0.45, 0.9 and 4.5 μM for PDE11, 6, 10, 5 and 8 respectively). Inhibits ENT1 and ENT2 (IC50 = 144.8 nM and Ki = 8.18 nM for ENT1).

Product Specifications for Dipyridamole

Molecular Weight

504.63

Formula

C24H40N8O4

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

2,6-bis(Diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine

CAS Number

58-32-2

PubChem ID

3108

InChI Key

IZEKFCXSFNUWAM-UHFFFAOYSA-N

SMILES

OCCN(CCO)C1=NC(N2CCCCC2)=C2N=C(N=C(N3CCCCC3)C2=N1)N(CCO)CCO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 100
Ethanol 10

Preparing Stock Solutions for Dipyridamole

The following data is based on the product molecular weight 504.63.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.98 mL 9.91 mL 19.82 mL
5 mM 0.40 mL 1.98 mL 3.96 mL
10 mM 0.20 mL 0.99 mL 1.98 mL
50 mM 0.04 mL 0.20 mL 0.40 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 37 publications citing the usage of this product.

Product Documents for Dipyridamole

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Dipyridamole

For research use only

Customer Reviews for Dipyridamole (1)

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  • pan ENT inhibitor
    Name: Timothy Ryan
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Primary hippocampal neurons
    Verified Customer | Posted 09/26/2025
    The drug was incubated at 1 μM to inhibit both ENT1 and ENT2 function.

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