DJ-V 159 New
Chemical Name: N1,N3-Bis(4-cyano-3-(trifluoromethyl)phenyl)isophthalamide
Biological ActivityGPRC6A agonist. Activates ERK and stimulates cAMP production in GPRC6A expressing HEK-293 cells. Stimulates insulin secretion from mouse β-cells in vitro. Reduces blood glucose levels in mice in vivo.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Computationally identified novel agonists for GPRC6A.
Pi et al.
PLoS One, 2018;13:e0195980
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