Chemical Name: N1,N3-Bis(4-cyano-3-(trifluoromethyl)phenyl)isophthalamide
Biological ActivityDJ-V 159 is a GPRC6A agonist. Activates ERK and stimulates cAMP production in GPRC6A expressing HEK-293 cells. Stimulates insulin secretion from mouse β-cells in vitro. Reduces blood glucose levels in mice in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Computationally identified novel agonists for GPRC6A.
Pi et al.
PLoS One, 2018;13:e0195980
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