(±)-AC 7954 hydrochloride

Key Product Details

Product Description

(±)-AC 7954 hydrochloride is a highly selective, non-peptide urotensin-II (UT) receptor agonist that displays potent activity at human and rat UT receptors (pEC₅₀ values are 6.5 and 6.7 respectively).

Product Specifications for (±)-AC 7954 hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for (±)-AC 7954 hydrochloride

The following data is based on the product molecular weight 366.28.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.75 mM	3.64 mL	18.20 mL	36.40 mL
3.75 mM	0.73 mL	3.64 mL	7.28 mL
7.5 mM	0.36 mL	1.82 mL	3.64 mL
37.5 mM	0.07 mL	0.36 mL	0.73 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Lavecchia Architecture of the human urotensin II receptor: comparison of the binding domains of peptide and non-peptide urotensin II agonists. J.Med.Chem. 2005 PMID: 15801838
• Lehmann Novel potent and efficacious nonpeptidic urotensin II receptor agonists. J.Med.Chem. 2006 PMID: 16570919
• Croston Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one (AC-7954). J.Med.Chem. 2002 PMID: 12408704

Product Documents for (±)-AC 7954 hydrochloride