Catalog Number: 0104
Chemical Name: DL-2-Amino-7-phosphonoheptanoic acid
Biological Activity
First generation phosphono NMDA antagonist. Anticonvulsant.
Technical Data
  • M.Wt:
    225.18
  • Formula:
    C7H16NO5P
  • Solubility:
    Soluble to 100 mM in 1eq. NaOH
  • Storage:
    Store at RT
  • CAS No:
    78966-69-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations.
    Evans et al.
    Br.J.Pharmacol., 1982;75:65
  2. Competitive NMDA antagonists as drugs.
    Meldrum and Chapman
    In The NMDA Receptor (2nd edition). Eds. G. L. Col, 1994;:457
Citations:

The citations listed below are publications that use Tocris products. Selected citations for DL-AP7 include:

2 Citations: Showing 1 - 2
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  1. Light-evoked NMDA receptor-mediated currents are reduced by blocking D-serine synthesis in the salamander retina.
    Authors: Stevens Et al.
    Neuroreport 2010;21:239
  2. Endogenous D-serine contributes to NMDA-receptor-mediated light-evoked responses in the vertebrate retina.
    Authors: Gustafson Et al.
    J Neurophysiol 2007;98:122

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