±-MF 094

Key Product Details

Product Description

±-MF 904 is the racemate of MF 904, the S-enantiomer. The S-enantiomer is a selective USP30 (ubiquitin-specific-processing protease 30) inhibitor (IC₅₀ = 120 nM). MF 094 increases protein ubiquitination and accelerates mitophagy.

Product Specifications for ±-MF 094

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for ±-MF 094

The following data is based on the product molecular weight 535.70.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	3.73 mL	18.67 mL	37.33 mL
2.5 mM	0.75 mL	3.73 mL	7.47 mL
5 mM	0.37 mL	1.87 mL	3.73 mL
25 mM	0.07 mL	0.37 mL	0.75 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Li and Liu Recent advances in the development of ubiquitin-specific-processing protease 7 (USP7) inhibitors. Eur.J.Med.Chem. 2020 PMID: 32092586
• Kluge Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg.Med.Chem.Lett. 2018 PMID: 29935771

Product Documents for ±-MF 094