DMSO, sterile filtered
Chemical Name: Dimethyl sulfoxide
Biological ActivityDMSO, sterile filtered is a solvent with wide ranging applications in cell culture, cryopreservation and organic chemistry. Dissolves both polar and nonpolar compounds. Improves responsiveness of human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) to differentiation signals. Used in PCR to inhibit secondary structure formation by DNA template or primers.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
A simple tool to improve pluripotent stem cell differentiation.
Chetty et al.
Citations for DMSO, sterile filtered
The citations listed below are publications that use Tocris products. Selected citations for DMSO, sterile filtered include:
17 Citations: Showing 1 - 10
Tofacitinib facilitates the expansion of myeloid-derived suppressor cells and ameliorates interstitial lung disease in SKG mice.
Authors: Sendo Et al.
Arthritis Res Ther 2019;21:184
Comparing Effects of Transforming Growth Factor β1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels.
Authors: Lively Et al.
Front Cell Neurosci 2018;12:115
Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells.
Authors: Morizane and Bonventre
Nat Protoc 2017;12:195
Relative Role of Akt, ERK and CREB in Alcohol-Induced Microglia P2X4R Receptor Expression.
Authors: Gofman Et al.
Alcohol Alcohol 2016;51:647
Thalamo-cortical axons regulate the radial dispersion of neocortical GABAergic interneurons.
Authors: Zechel Et al.
The novel protein kinase C ε isoform modulates acetylcholine release in the rat neuromuscular junction.
Authors: Obis Et al.
J Neurophysiol 2015;8:80
The novel protein kinase C ε isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release.
Authors: Obis Et al.
PLoS One 2015;8:8
Influenza induces IL-8 and GM-CSF secretion by human alveolar epithelial cells through HGF/c-Met and TGF-α/EGFR signaling.
Authors: Ito Et al.
Mol Brain 2015;308:L1178
The development of zebrafish tendon and ligament progenitors.
L-type Ca2+ channel responses to bay k 8644 in stem cell-derived cardiomyocytes are unusually dependent on holding potential and charge carrier.
Authors: Ji Et al.
Assay Drug Dev Technol 2014;12:352
The dorsomedial hypothalamus mediates stress-induced hyperalgesia and is the source of the pronociceptive peptide cholecystokinin in the rostral ventromedial medulla.
Authors: Wagner Et al.
Am J Physiol Lung Cell Mol Physiol 2013;238:29
Endogenous analgesic action of the pontospinal noradrenergic system spatially restricts and temporally delays the progression of neuropathic pain following tibial nerve injury.
Authors: Hughes Et al.
Mol Brain 2013;154:1680
Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation.
Authors: Hermanson Et al.
J Neuroendocrinol 2012;7:e43580
Photoperiodic changes in endocannabinoid levels and energetic responses to altered signalling at CB1 receptors in Siberian hamsters.
Authors: Ho Et al.
Behav Brain Res 2012;24:1030
Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4+ T cells to T-regulatory cells.
Authors: Olkhanud Et al.
Cancer Res 2011;71:3505
GABA actions in hippocampal area CA3 during postnatal development: differential shift from depolarizing to hyperpolarizing in somatic and dendritic compartments.
Authors: Romo-Parra Et al.
Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation.
Authors: Andäng Et al.
What type of vial is Catalog # 3176, DMSO, supplied in?
The 5 mL and 25 mL size products are supplied in 5 mL glass vials. The 100 mL product is supplied in a 100 mL glass vial.
Reviews for DMSO, sterile filtered
Average Rating: 5 (Based on 2 Reviews)
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We use DMSO for cryopreservation of HBECs - 92.5% of complete growth medium (containing DMEM/F12, 10% FBS, 1% penicillin-streptomycin and 40 µg/mL endothelial growth supplement) : 7.5% of DMSO. Cells grow well after thawing.
DMSO is used for dissolving CHIR (4423).Reconstitute 10 mg of CHIR in 2.149 ml of DMSO for a final concentration of 10mM.