DMSO, sterile filtered

Catalog # Availability Size / Price Qty
DMSO, sterile filtered | CAS No. 67-68-5 | Buffers, Chelators and Reagents
1 Image
Description: DMSO, sterile filtered, wide ranging applications in cell culture, cryopreservation and organic chemistry. Solvent for polar and nonpolar compounds
Alternative Names: Methyl sulfoxide

Chemical Name: Dimethyl sulfoxide

Purity: ≥99.9%

Product Details
Citations (17)
Reviews (2)

Biological Activity

DMSO, sterile filtered is a solvent with wide ranging applications in cell culture, cryopreservation and organic chemistry. Dissolves both polar and nonpolar compounds. Improves responsiveness of human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) to differentiation signals. Used in PCR to inhibit secondary structure formation by DNA template or primers.

Technical Data

Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A simple tool to improve pluripotent stem cell differentiation.
    Chetty et al.
    Nat.Methods, 2013;10:553

Product Datasheets

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Citations for DMSO, sterile filtered

The citations listed below are publications that use Tocris products. Selected citations for DMSO, sterile filtered include:

17 Citations: Showing 1 - 10

  1. Tofacitinib facilitates the expansion of myeloid-derived suppressor cells and ameliorates interstitial lung disease in SKG mice.
    Authors: Sendo Et al.
    Arthritis Res Ther  2019;21:184
  2. Comparing Effects of Transforming Growth Factor β1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels.
    Authors: Lively Et al.
    Front Cell Neurosci  2018;12:115
  3. Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells.
    Authors: Morizane and Bonventre
    Nat Protoc  2017;12:195
  4. Relative Role of Akt, ERK and CREB in Alcohol-Induced Microglia P2X4R Receptor Expression.
    Authors: Gofman Et al.
    Alcohol Alcohol  2016;51:647
  5. Thalamo-cortical axons regulate the radial dispersion of neocortical GABAergic interneurons.
    Authors: Zechel Et al.
    Elife  2016;5
  6. The novel protein kinase C ε isoform modulates acetylcholine release in the rat neuromuscular junction.
    Authors: Obis Et al.
    J Neurophysiol  2015;8:80
  7. The novel protein kinase C ε isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release.
    Authors: Obis Et al.
    PLoS One  2015;8:8
  8. Influenza induces IL-8 and GM-CSF secretion by human alveolar epithelial cells through HGF/c-Met and TGF-α/EGFR signaling.
    Authors: Ito Et al.
    Mol Brain  2015;308:L1178
  9. The development of zebrafish tendon and ligament progenitors.
    Authors: Chen
    Development  2014;141:2035
  10. L-type Ca2+ channel responses to bay k 8644 in stem cell-derived cardiomyocytes are unusually dependent on holding potential and charge carrier.
    Authors: Ji Et al.
    Assay Drug Dev Technol  2014;12:352


  1. What type of vial is Catalog # 3176, DMSO, supplied in? 

    • The 5 mL and 25 mL size products are supplied in 5 mL glass vials. The 100 mL product is supplied in a 100 mL glass vial. 

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Reviews for DMSO, sterile filtered

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DMSO for cryopreservation of HBECs
By Angie Sin on 01/25/2021
Application: Species: Human

We use DMSO for cryopreservation of HBECs - 92.5% of complete growth medium (containing DMEM/F12, 10% FBS, 1% penicillin-streptomycin and 40 µg/mL endothelial growth supplement) : 7.5% of DMSO. Cells grow well after thawing.

To dissolve CHIR for kidney differentiation from iPSC
By Pinyuan Tian on 08/07/2018
Application: Species: Human

DMSO is used for dissolving CHIR (4423).Reconstitute 10 mg of CHIR in 2.149 ml of DMSO for a final concentration of 10mM.

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