Chemical Name: 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acid
Biological Activity mSTING agonist; selective for mouse STING over human STING. Induces IFN-β and cytokine production from bone marrow-derived dendritic cells. Causes tumor regression following intratumoral administration in mouse tumor models. Induces an adaptive immune response to reduce systemic tumor growth and provides immunological memory against autologous tumor re-challenge. Also antiviral.
Soluble to 20 mM in DMSO
Store at +4°C
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