DMXAA

   
Product Datasheet
Catalog Number:5601
Chemical Name:5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acid
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Biological Activity
mSTING agonist; selective for mouse STING over human STING. Induces IFN-β and cytokine production from bone marrow-derived dendritic cells. Causes tumor regression following intratumoral administration in mouse tumor models. Induces an adaptive immune response to reduce systemic tumor growth and provides immunological memory against autologous tumor re-challenge. Also antiviral.
Technical Data
  • M.Wt:
    282.29
  • Formula:
    C17H14O4
  • Solubility:
    Soluble to 20 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    117570-53-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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VersaClone cDNA Plasmids
Description Application Cat# Citations Images  

Mouse IFN-beta (NP_034640) VersaClone cDNA

RDC2368
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