DMXAA

Catalog # Availability Size / Price Qty
5601/10
5601/50
Cat.No. 5601 - DMXAA | C17H14O4 | CAS No. 117570-53-3
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Description: mSTING agonist; induces antitumor immunological responses

Chemical Name: 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acid

Purity: ≥99%

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Biological Activity

mSTING agonist; selective for mouse STING over human STING. Induces IFN-β and cytokine production from bone marrow-derived dendritic cells. Causes tumor regression following intratumoral administration in mouse tumor models. Induces an adaptive immune response to reduce systemic tumor growth and provides immunological memory against autologous tumor re-challenge. Also antiviral.

Technical Data

M.Wt:
282.29
Formula:
C17H14O4
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
117570-53-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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