Chemical Name: 3,4-Dihydroxyphenethylamine hydrochloride
Biological ActivityDopamine hydrochloride is an endogenous neurotransmitter that acts as an agonist at dopamine D1-5 receptors. Synthesized in the substantia nigra and ventral tegmental area, and is a precursor in noradrenalin and adrenalin biosynthesis.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Novel insights into DA receptor pharmacology.
Rivonello et al.
Role of DA in the motivational and cognitive control of behavior.
Prolactin and DA: what is the connection? A review article.
Fitzgerald and Dinan
Citations for Dopamine hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Dopamine hydrochloride include:
21 Citations: Showing 1 - 10
Autoregulation of GPCR signalling through the third intracellular loop.
Authors: Ning Et al.
Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors.
Authors: Kira E Et al.
Cell Rep 2022;40:111426
Agonist and antagonist TRUPATH assays for G protein-coupled receptors.
Authors: Bryan L Et al.
STAR Protoc 2022;3:101259
History-dependent dopamine release increases cAMP levels in most basal amygdala glutamatergic neurons to control learning.
Authors: Mark L Et al.
Cell Rep 2022;38:110297
Bingeing on High-Fat Food Enhances Evoked Dopamine Release and Reduces Dopamine Uptake in the Nucleus Accumbens.
Authors: Sara R Et al.
Obesity (Silver Spring) 2021;29:721-730
Expression of FoxP2 in the basal ganglia regulates vocal motor sequences in the adult songbird.
Authors: Mou Et al.
Nat Commun 2021;12:2617
New phosphosite-specific antibodies to unravel the role of GRK phosphorylation in dopamine D2 receptor regulation and signaling.
Authors: Stefan Et al.
Sci Rep 2021;11:8288
Cerebellar modulation of synaptic input to freezing-related neurons in the periaqueductal gray.
Authors: Spencer T Et al.
Identification of Mubritinib (TAK 165) as an inhibitor of KSHV driven primary effusion lymphoma via disruption of mitochondrial OXPHOS metabolism.
Authors: Fang Et al.
Dopaminergic Transmission Rapidly and Persistently Enhances Excitability of D1 Receptor-Expressing Striatal Projection Neurons.
Authors: Mark D Et al.
Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses.
Authors: Thomas C Et al.
DA D4 receptor activation restores CA1 LTP in hippocampal slices from aged mice.
Dopamine D4 receptor activation restores CA1 LTP in hippocampal slices from aged mice. 2017;16(6):1323
Endogenous 17β-OE is required for activity-dependent long-term potentiation in the striatum: interaction with the DArgic system.
Authors: Tozzi Et al.
Front Cell Neurosci 2015;9:192
Retroactive modulation of spike timing-dependent plasticity by DA.
Authors: Brzosko Et al.
Pronociceptive and Antinociceptive Effects of Bupren. in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude.
Authors: Gerhold Et al.
J Neurosci 2015;35:9580
Palatability Can Drive Feeding Independent of AgRP Neurons.
Authors: Bénédicte Et al.
Cell Metab 2015;22:646-57
Attenuated DArgic tone in the paraventricular nucleus contributing to sympathoexcitation in rats with Type 2 diabetes.
Authors: Zheng Et al.
Physiol Res 2014;306:R138
Sucrose produces withdrawal and DA-sensitive reinforcing effects in planarians.
Authors: Zhang Et al.
Physiol Behav 2013;112-113:8
Dependence of spontaneous electrical activity and basal prolactin release on nonselective cation channels in pituitary lactotrophs.
Authors: Kucka Et al.
World J Gastroenterol 2012;61:267
Dopamine induces LTP differentially in apical and basal dendrites through BDNF and voltage-dependent calcium channels.
Authors: Martin Et al.
Learn Mem 2012;19:294-9
DA-induced proliferation of adult neural precursor cells in the mammalian subventricular zone is mediated through EGF.
Authors: O'Keeffe Et al.
Proc Natl Acad Sci U S A 2009;106:8754
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